Ampakines


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Research into Ampakines

Neuroplasticity Underlying the Comorbidity of Pain and Depression.

Drug repurposing and emerging adjunctive treatments for schizophrenia.

Ampakines Enhance Weak Endogenous Respiratory Drive and Alleviate Apnea in Perinatal Rats.

Cisplatin Causes Mitochondrially Mediated Hippocampal Damage.

Coadministration of the AMPAKINE CX717 with Propofol Reduces Respiratory Depression and Fatal Apneas.

Combined ampakine and BDNF treatments enhance poststroke functional recovery in aged mice via AKT-CREB signaling.

New Therapy for Apnea of Prematurity?

AMPAkines Have Novel Analgesic Properties in Rat Models of Persistent Neuropathic and Inflammatory Pain.

Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memory.

Ampakines Enhance Respiratory Motor Output In A Murine Model Of Pompe Disease.

Ampakines induce a persistent increase in phrenic motor output in rats with cervical spinal cord injury.

Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals

Opiate-induced suppression of rat hypoglossal motoneuron activity and its reversal by ampakine therapy.

Ampakines Stimulate Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease.

Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice.

Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia.

Performance enhancement at the cost of potential brain plasticity: neural ramifications of nootropic drugs in the healthy developing brain.

Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals

Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice.

AMPAKINE enhancement of social interaction in the BTBR mouse model of autism

Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting.

Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals

Ampakine therapy to counter fentanyl-induced respiratory depression.

Ampakine CX717 protects against fentanyl-induced respiratory depression and lethal apnea in rats.

Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers.

Ampakine (CX717) effects on performance and alertness during simulated night shift work.

Cortex Pharmaceuticals, Inc. Says Drug Falls Short In Study

Glutamatergic drugs for schizophrenia

Drug offsets sleep deprivation effects, in monkeys

Cosmetic Neurology: For Physicians the Future is Now

Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates

Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor.

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